CALABRESE Vittorio
Professore Ordinario
Settore scientifico disciplinare di riferimento
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Biochimica clinica e biologia molecolare clinica (BIOS-09/A)
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Ateneo
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Università degli Studi di CATANIA
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Struttura di afferenza
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Dipartimento di
SCIENZE BIOMEDICHE E BIOTECNOLOGICHE
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E-Mail |
calabres@unict.it |
E-Mail |
vittorio.calabrese@unict.it |
Orari di ricevimento
Martedì e Giovedì ore 10.00-12.00
Curriculum
Prof. Vittorio Calabrese, Graduated in Medicine on 1984 at the University of Catania, after specialization in Neurology, on 1988 at University of Catania, since 1996 was Researcher at the Department of Biochemistry, School of Medicine, University of Catania. By 2001 to date Prof. Calabrese is a Professor of Clinical Biochemistry at the School of Medicine and Surgery and actual Director of School of Specialization in Clinical Pathology and Clinical Biochemistry, University of Catania and University of Messina. He is member of the Editorial Board of several high peer reviewed journals including: Journal of Neuroscience Research; Neurochem Research; Antioxidant Redox Signaling; Journal Neurochemistry; Free Radical Biology Medicine; Current Neurovascular Disorders. He has been reviewer of national projects (Italian MIUR), and many foreign projects for foreign institutions. He has been member of the ASN Commission (05/E1) of the Italian MIUR for the year 2013 and 2014. He is member GEV -Area 5 - Scienze biologiche -for the year 2020-2022, as well as member AVA (ANVUR) for the year 2021-2022. His research focuses on the role of free radicals and antioxidants in human disease, particularly Alzheimer's disease and other brain disorders. His interest in identifying the most important antioxidants in the human diet and in developing novel antioxidants has critical bearing on treating human diseases and understanding how diet might cause or prevent them. Areas of his research interests includes role of Oxidative Stress and Mitochondrial dysfunction in Aging, Neurodegenerative disorders and Longevity; Proteomics and redox proteomics, Heat shock signal pathway Hormesis and Vitagenes in Neurodegeneration. The results of his researches have been reported in over 281 scientific papers published in outstanding international journals and widely cited (around 18165 total citations), for an h Index value of 85 (ISI). He has deposited the patents (Nr. WO 2004/07883 A1 of 10.9.2004) for the use of curcumin and its derivatives in the treatment neurodegenerative disorders; and (Nr. US20040167217) Neuroprotective effects of polyphenolic compounds.
Actual Position
• Full Professor Clinical Biochemistry and Clinical Molecular Biology, School of Medicine, University of Catania, Department of Biomedical and Biotechnological Sciences University of Catania. Via Santa Sofia, 97 - 95125 - Catania - E-mail: calabres@unict.it.
• Director School of Specialization Clinical Pathology and Clinical Biochemistry, Faculty of Medicine, University of Catania and University of Messina.
• Member of International Doctorate in Neurosciences, University of Catania, University of Catania.
Previous experiences
• 1987 Post-Doctoral fellow in Neurobiology at the New York University Medical School, (N.Y.);
• 1989 Post-Doctoral fellow in Neuropharmacology at the Thomas Jefferson University Medical School (Philadelphia, PA,);
• 2000-2005: Visiting Professor University College London, Department of Neurochemistry, funded by Wellcome Trust Grant on “The role of antioxidants in L-DOPA induced damage to the Substantia Nigra”.
• Visiting Professor Northwick Park Institute for Medical Research, Department of Surgical Research, University of London;
• Visiting Professor University of Kentucky, Department of Chemistry.
• Visiting Professor Blanchette Rockefeller Neuroscience Institute, West Virginia University (MD).
• Coordinator Euro-Mediterranean- Academy of Antiaging Medicine
• Visiting Professor Biomedical Research Centre, University of Dundee (UK).
• Visiting Professor Barshop Institute for Aging and Longevity Studies, Department of Physiology, University of Texas Health Science Center, San Antonio, TX.
• Visiting Professor Department of Pediatrics, University Hospital Heidelberg, Germany.
• Visiting Professor Institute of Biology and Molecular Genetics, Humboldt University of Berlin, Germany.
• Visiting Professor, Department of Environmental Health Sciences, University of Massachusetts, Amherst, MA
Study Career
• 04/09/1984 Laurea in Medicina, magna cum laude, University of Catania, Thesis: Lipid Metabolism During Aging.
• 07/08/1988 Specialization in Neurologia, magna cum laude, University of Catania. Thesis: Oxidative Stress in CNS.
• 04/08/1996 Researcher SSD BIO10
• 17/9/2001 Associate Professor
• 5/9/2006 Abilitation to Full Professor SSD BIO12 (DR n. 10144 del 2006/05/09 University of Bari).
• 1/11/2010 Nomination Full Professor Clinical Biochemistry SSD BIO12 (DR n. 2268 del 22.4.2011, University of Catania.
Fields of Scientific interests
Role of Oxidative Stress and Mitochondrial dysfunction in Aging, Neurodegenerative disorders and Longevity
2. Nutritional Antioxidants and Modulation of cellular redox state.
3. Proteomics and redox proteomics
4. Heat shock signal pathway and brain cell stress response
5. Alcohol metabolism and alcohol-related pathology
6. Gasobiology of the CNS: Role of Nitric Oxide (NO), Carbon Monoxide (CO) and Hydrogen sulfite (H2S) in the regulation of gene expression
7. Carbon monoxide and organ transplantation
8. Redox Modulation of Vitagenes by endogenous compounds (Carnosine, Carnitines, Hormones) by polyphenols as target for nover therapeutic interventions in neurodegeneration and cancer.
9. Hormesis and Hormetic Nutrition;
10. Antiaging Medicine and Mitochondrial Medicine
10. Minibrain e Organoid technology: Organ-on-a-Chip.
Editorial Memberships
Editor in Chief
1. Open Medicine
Editor Member
1. J. Neuroscience Research
2. Neurochemical Research
3. Antioxidant Redox Signaling
4. Journal Neurochemistry
5. Free Radical Biology Medicine
6. Current Neurovascular Disorders.
7. Antioxidants
8. Int. J. Mol. Sciences
9. Biochemical Pharmacology
10. Journal Neuroscience Research
11. Faseb Journal
12. Journal of Biological Chemistry
13. Mechanisms of Ageing and Development
14. Antioxidant Redox Signaling
Publications
1. Ragusa N., Sfogliano L., Calabrese V., and Rizza V. (1981). Effects of multivitamin treatment on the activity of rat liver triptophan pyrrolase during ethanol administration. Acta Vitaminologica et Enzimologica 3,(4), 199-204.
2. Calabrese V., Guerrera F., Avitabile M., Famà M., and Rizza V. (1984). Superoxide dismutase and reduced glutathione: possible defense operating in hyperoxic swimbladder of fish. In: Toxin, drugs and pollutans in marine animals. (eds. Bolis et al.) pp. 130-136. Springer-Verlag, Berlin.
3. Calabrese V., Fariello R.G. (1988). Regional distribution of malonaldehyde in mouse brain. Biochemical Pharmacology, 37,11, 2287-2288.
4. Rizza V., Lorefice R., Rizza N., and Calabrese V. (1992). Pharmacokinetics of L-carnitine in human subjects. In: L-carnitine and its role in medicine: from function to therapy, (eds. Ferrari R., Dimauro S., Sherwood G.) pp. 63-77. Academic Press, New York.
5. Milazzo G., Rizza V., Mangiameli S., Di Stefano A., Cantarella G., Niceforo A., Ricciardi R., Calabrese V. (1992) Oxygen free radical pathology: Role of exogenous antioxidants (GSH) in anesthesia. Acta Anaesthesiologica Italica, 43, 330-337.
6. Calabrese V., Bombaci G., Calderone A., Rizza, V. (1993) Effects of metadoxine on cellular free fatty acid levels in ethanol treated rats. Int. J. Tissue Reactions, 15, 235-243.
7. Calabrese V., Renis M., Calderone A., Russo A., Barcellona M.L., Rizza V. (1996) Stress proteins and SH-groups in oxidant-induced cell damage after acute ethanol administration in rat. Free Radical Biology and Medicine 20, 391-397.
8. Renis M., Calabrese V., Russo A., Calderone A., Barcellona M.L., Rizza V. (1996) Nuclear DNA strand breaks during ethanol-induced oxidative stress in rat brain. FEBS Letters 390, 153-156.
9. Calabrese V., Renis M., Calderone A., Russo A., Reale S., Barcellona M.L., Rizza V. (1998) Stress proteins and SH-groups in oxidant-induced cell injury after chronic ethanol administration in rat. Free Radical Biology and Medicine 24, 1159-1167.
10. Calabrese V., Rizza V. (1999) Formation of propionate after short-term ethanol treatment and its interaction with the carnitine pool in rat. Alcohol 19, 169-176.
11. Pennisi G., Rapisarda G., Bella R., Calabrese V., Maertens de Noordhout A., Delwaide P.J. (1999) Absence of response to early transcranial magnetic stimulation in ischemic stroke patients. Stroke 30, 2666-2670.
12. Calabrese V., Rizza V. (1999) Effects of l-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat. Neurochem. Res. 24, 79-84.
13. Calabrese V., Randazzo G., Ragusa N., Rizza V. (1998) Long-term ethanol administration enhances age-dependent modulation of redox state in central and peripheral organs of rat: Protection by metadoxine. Drugs Exp. Clin. Research, 24, 85-91.
14. Calabrese V., Spadaro F., Dinotta F., Ravagna A., Randazzo F., Randazzo G., Ragusa N., Rizza V. (1998) Long-term ethanol administration enhances urinary ultraweak luminescence and age-dependent modulation of redox in central and peripheral organs of the rat. Int. J. of Tissue Reactions, 20, 57-62.
15. Calabrese V., Randazzo S.D., Catalano C., Rizza V. (1999) Biochemical studies on a novel antioxidant from lemon oil and its biotechnological application in cosmetic dermatology. Drugs Exp. Clin. Research, 25, 219-225.
16. Calabrese V., Randazzo S.D., Morganti P.G., Rizza V. (1999) An ex vivo biochemical model to study the antioxidant clinical properties of cosmetic products in human antiaging skin care. Drugs Exp. Clin. Research, 25, 43-49.
17. Calabrese V., Testa D., Ravagna A., Bates T.E., A.M. Giuffrida Stella. (2000) HSP70 induction in the brain following ethanol administration in the rat: regulation by glutathione redox state. Biochem. Biophys. Res. Comm. 269, 397-400.
18. Calabrese V., Copani A., Testa D., Ravagna A., Spadaro F., Tendi E., Nicoletti V., A.M. Giuffrida Stella. (2000) Nitric oxide synthase induction in astroglial cell cultures: Effect on heat shock protein 70 synthesis and oxidant / antioxidant balance. J. Neurosci. Res. 60, 613-622.
19. Motterlini R., Foresti R., Bassi R., Calabrese V., Clark J.E., Green C.J. (2000) Endothelial Heme oxygenase-1 induction by hypoxia: modulation by inducible nitric oxide synthase (iNOS) and S-nitrosothiols. J. Biol. Chem. 275, 13613-13620.
20. Calabrese V., Scapagnini G., Catalano C., Dinotta F., Geraci D., Morganti P. (2000) Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology. Int. J. Tissue Reactions 22, 5-13.
21. Calabrese V., Bates T.E., Giuffrida Stella A.M. (2000) NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res. 65, 1315-1341.
22. Calandra C., Musumeci G., Mangiameli A., Calabrese V. (2000) Perception of alcoholism problem among young people between 13 and 30 years old. Eur. J. of Alcohol Studies 12, 85-89.
23. Scapagnini G., Dinotta F, Calabrese V. (2000) Oxidative stress and Neurodegenerative Disorders: The role of Vitamion E in Nutritional Neuroscience. Int. J. Immunopathol. Immunopharmacology 1, 97-107.
24. Calabrese V., Scapagnini G., Catalano D., Dinotta F., Bates T.E., Calvani M, Giuffrida Stella A.M. (2001) Effects of acetyl-l-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat. Neurochem. Res. 26, 167-174.
25. Calabrese, V., Scapagnini G., Catalano C., Bates T.E., Dinotta F., Micali G., A.M. Giuffrida Stella (2001) Induction of heat shock protein synthesis in human skin fibroblasts in response to oxidative stress: regulation by a natural antioxidant from rosemary extract. Int. J. Tissue Reactions 23, 51-58.
26. Calabrese, V., Scapagnini G., Giuffrida Stella A.M., Bates T.E., Clark J.B., (2001) Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem. Res. 26, 739-764.
27. Calabrese, V., Scapagnini G., Catalano C., Bates T.E., Geraci D., Pennisi G., Giuffrida Stella A.M. (2001) Induction of heat shock protein synthesis in human skin fibroblasts in response to oxidative stress: regulation by Vitamin E. Int. J. Tissue Reactions 23, 127-135.
28. Anello M, Ucciardello V, Piro S, Patane G, Frittitta L, Calabrese V, Giuffrida Stella AM, Vigneri R, Purrello F, Rabuazzo AM. (2001) Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio. Am. J. Physiol. Endocrinol. Metab. 281, E1082-1087.
29. Calabrese V., Scapagnini G., Ravagna A., Giuffrida Stella A., Butterfield A. (2002) Molecular chaperones and their roles in neural cell ifferentiation. Dev. Neurosci. 24, 40-56.
30. Calabrese V., Scapagnini G., Ravagna A., Fariello R.G., Giuffrida Stella AM. and Abraham N. (2002) Regional distribution of heme oxygenase, hsp70, and glutathione in brain: relevance for endogenous oxidant / antioxidant balance and stress tolerance. J. Neurosci. Res. 68, 65-75.
31. Butterfield D.A., Castegna A., Drake J., Scapagnini G., Calabrese V. (2002) Vitamin E and neurodegenerative disorders associated with oxidative stress. Nutr. Neurosci. 4, 229-239.
32. Butterfield D., Castegna A., Pocernich C., Drake J., Scapagnini G., Calabrese V. (2002) Nutritional approaches to combat oxidative stress in Alzheimer's disease. J. Nutr. Biochem. 13, 444-461.
33. Scapagnini G., Foresti R., Calabrese V., Giuffirida Stella A.M., Green C.J., Motterlini R. (2002) Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers. Mol Pharmacol 61, 554-561.
34. Scapagnini G., Giuffrida Stella A.M., Abraham N.G., Alkon D., Calabrese V. (2002) Differential expression of Heme oxygenase-1 in rat brain by endotoxin (LPS). In: Heme Oxygenase in Biology and Medicine (Abraham et al., eds.) pp. 121-134, Kluwer Academic Plenum Publisher, N.Y.
35. Calabrese V., Scapagnini G., Ravagna A., Bella R., Foresti R., Bates T.E., Giuffrida Stella A.M., Pennisi G. (2002) Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in CSF protein nitrotyrosine, S-nitrosothiols and with changes in glutathione levels. J. Neurosci. Res. 70, 580-587.
36. Scapagnini G., D'Agata V., Calabrese V., Pascale A., Colombrita C., Alkon D., Cavallaro S. (2002) Gene expression profiles of heme oxygenase isoforms in the rat brain. Brain Res. 954, 51-59.
37. Calabrese V., Scapagnini G., Latteri S., Colombrita C., Ravagna A., Catalano C., Pennisi G., Calvani M., Butterfield D.A. (2002) Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. Int. J. Tissue Reactions 24, 97-104.
38. Scapagnini G., Ravagna A., Bella R., Colombrita C., Pennisi G., Calvani M., Alkon D., Calabrese V. (2002) Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine. Int. J. Tissue Reactions. 24, 89-96.
39. Calabrese V., Scapagnini G., Latteri S., Butterfield D.A., Scapagnini U. Heme oxygenase, carbon monoxide and Cellular Stress Response in the Nervous System: The good and the enigmatic. (2002) Neurochemistry News 2, 57-60.
40. Colombrita C., Calabrese V., Stella A.M., Mattei F., Alkon D.L., Scapagnini G. (2003) Regional rat brain distribution of heme oxygenase-1 and manganese superoxide dismutase mRNA: relevance of redox homeostasis in the aging processes. Exp. Biol. Med. 228, 517-524.
41. Catania M.V., Giuffrida R., Seminara G., Barbagallo G., Aronica E., Gorter J.A., Dell'Albani P., Ravagna A., Calabrese V., Giuffrida-Stella A.M. (2003) Upregulation of neuronal nitric oxide synthase in in vitro stellate astrocytes and in vivo reactive astrocytes after electrically induced status epilepticus. Neurochem. Res 28, 607-615.
42. Calabrese, V., Scapagnini, G., Ravagna, A., Bella, R., Butterfield, D.A., Calvani, M., Pennisi, G., Giuffrida Stella, A.M.. (2003). Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine. Neurochem. Res. 28, 1321-1328.
43. Drake J., Sultana R., Aksenova M., Calabrese V., Butterfield DA. (2003). Elevation of mitochondrial glutathione by gamma-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress. J. Neurosci. Res. 74, 917-927.
44. Calabrese V., Scapagnini G., Colombrita C., Ravagna A., Pennisi G., Giuffrida Stella A.M., Galli F., Butterfield DA. (2003). Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach. Amino Acids 25, 437-444.
45. Calabrese V., Butterfield D.A., Giuffrida Stella A.M. (2003) Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. Italian Journal of Biochemistry 52, 72-76.
46. Calabrese V., Scapagnini G., Ravagna A., Colombrita C., Spadaro F., Butterfield D.A., Giuffrida Stella A.M. (2004). Increased expression of heat shock proteins in rat brain during aging: relationship with mitochondrial function and glutathione redox state. Mech. Age Dev. 125, 325-335.
47. Poon H.F., Calabrese V., Scapagnini G., Butterfield D.A. (2004) Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. J. Gerontology A 59, 478-493.
48. Poon H.F., Calabrese V., Scapagnini G., Butterfield D.A. (2004). Free radicals and brain aging. Clin. Geriatr. Med. 20, 329-359.
49. Pocernich C.B., Sultana R., Hone E., Turchan J., Martins R.N., Calabrese V., Nath A., Butterfield D.A. (2004). Effects of apolipoprotein E on the human immunodeficiency virus protein tat in neuronal cultures and synaptosomes. J. Neurosci. Res. 77, 532-539.
50. Poon H.F., Joshi G., Sultana R., Farr S.A., Banks W.A., Morley J.E., Calabrese V., Butterfield D.A. (2004). Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice. Brain Res. 1018, 86-96.
51. Calabrese V., Giuffrida Stella AM, Butterfield DA, Scapagnini G. (2004) Redox Regulation in Neurodegeneration and Longevity: Role of the Heme Oxygenase and HSP70 Systems in Brain Stress Tolerance. Antioxid Redox Signal. 6, 895-913.
52. Scapagnini G, Butterfield DA, Colombrita C, Sultana R, Pascale A, Calabrese V. (2004) Ethyl Ferulate, a Lipophilic Polyphenol, Induces HO-1 and Protects Rat Neurons Against Oxidative Stress. Antioxid Redox Signal. 6, 811-818.
53. Calabrese V., Boyd-Kimball D, Scapagnini G, Butterfield DA. (2004) Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of vitagenes. In Vivo. 18, 245-268.
54. Calabrese V., Calvani M, Butterfield DA. (2004). Increased formation of short-chain organic acids after chronic ethanol administration and its interaction with the carnitine pool in rat. Arch. Biochem. Biophys. 431, 271-278.
55. Calabrese V., Ravagna A., Colombrita C., Guagliano E., Scapagnini G., Calvani M., Butterfield D.A., Giuffrida Stella A.M. (2005) Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2. J. Neuroscience Research 79, 509-521.
56. Sultana R., Ravagna A., Mohmmad-Abdul H., Calabrese V., Butterfield D.A. (2005) Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J. Neurochem. 92, 749-758.
57. Pocernich C., Boyd-Kimball D., Poon F., Thongboonkerd V., Lynn B.C., Calabrese V., Nath A., Butterfield D.A. (2005) Proteomic analysis of human Astrocytes expressing the HIV protein TAT. Brain Res. (Mol Brain Res). 133, 307-316.
58. Poon H.F., Hensley K., Thingboonkerd V., Merchant M.L., Lynn B.C., Pierce W.M., Knlein J.B., Calabrese V., Butterfeild D.A. (2005) Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis. Free Rad. Biol. Med. 39, 453-462.
59. Perluigi M., Poon H.F., Hensley K., Pierce W.M., Klein J.B., Calabrese V., De Marco C., Butterfield D.A. (2005) .Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice-A model of familial amyotrophic lateral sclerosis. Free Radic. Biol. Med. 38, 960-968.
60. Poon H.F., Frasier M., Shreve N., Calabrese V., Wolozin B., Butterfield D.A. (2005) Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiol. Dis. 18, 492-498.
61. Calabrese V., Ravagna A., Scapagnini G., Catalano C., Pennisi G., Butterfield D.A., Giuffrida Stella A.M. (2005) Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich Ataxia. J. Neurol Sci. 233, 145-162.
62. Calabrese V., Colombrita C., Guagliano E., Sapienza M., Ravagna A., Tomaselli G., Cardile V. Scapagnini G., Butterfield D.A., Giuffrida Stella A.M., and Rizzarelli E.. (2005) Protective effect of carnosine during nitrosative stress in astroglial cell cultures. Neurochem. Res. 30, 797-807.
63. Perluigi M., Poon H.F., Maragos W., Pierce WM., JB Klein JB, Calabrese V., Cini C., De Marco C., Butterfield D.A., (2005). Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice--A Model of Huntington's Disease. Molecular and Cellular Proteomics, 4, 1849-1861.
64. Poon H.F., Shepherd H.M., Reed T., Calabrese V., Giuffrida-Stella A.M., Pennisi G., Cai J., Pierce W.M., ; Klein J.B., Butterfield D.A: (2006) Proteomics Analysis Provides Insight into Caloric Restriction-Mediated Reduced Oxidation and Altered Expression of Brain Proteins Associated with Age-related Impaired Cellular Processes: Mitochondrial Dysfunction, Glutamate Dysregulation and Impaired Protein Synthesis. Neurobiology of Aging 27, 1020-1034.
65. Calabrese V., Pennisi G., Calvani M., Giuffrida Stella A.M., Butterfield D.A., Mancuso C. (2006) Heme Oxygenase As Therapeutic Funnel in Nutritional Redox Homeostasis and Cellular Stress Response: Role of Acetylcarnitine. In: Heat Shock Protein in Neural Cells, Christiane Ritcher-Landsberg Eds., Eurekah.com
66. Calabrese V., Colombrita C., Scapagnini G., Calvani M., Giuffrida Stella AM., Butterfield D.A. (2006) Acetylcarnitine and cellular stress response: role in nutritional redox homeostasis and regulation of longevity genes. J. Nutr. Biochemistry 17,73-88.
67. Perluigi M., Joshi G, Sultana R., Calabrese V., De Marco C., Coccia R., Butterfield D.A. (2006) In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid beta-peptide (1-42)-induced oxidative stress. Neuroscience 138, 1161-1170.
68. Joshi G., Perluigi M., Sultana R., Agrippino R., Calabrese V., Butterfield D.A. (2006) In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders. Neurochem. Int. 48,:318-327.
69. Calabrese V., Butterfield D.A., Scapagnini G., Stella A.M., Maines M.D. (2006) Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity. Antioxid Redox Signal. 8, 444-477.
70. Lodi R., Tonon C., Calabrese V., Schapira A.H. (2006) Friedreich's Ataxia: From Disease Mechanisms to Therapeutic Interventions. Antioxid Redox Signal. 8, 438-443.
71. Calabrese V., Colombrita C., Sultana R., Scapagnini G., Calvani M., Butterfield D.A., Stella A.M. (2006) Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. Antioxid Redox Signal. 8, 404-416.
72. Scapagnini G., Colombrita C., Amadio M., D'Agata V., Arcelli E., Sapienza M., Quattrone A., Calabrese V. (2006) Curcumin activates defensive genes and protects neurons against oxidative stress. Antioxid Redox Signal. 8, 395-403.
73. Calabrese V., Maines M.D. (2006) Antiaging medicine: antioxidants and aging. Antioxid Redox Signal. 8, 362-364.
74. Poon H.F., Calabrese V., Calvani M., Butterfield D.A. (2006) Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. Antioxid Redox Signal. 8, 381-394.
75. Abdul H.M., Calabrese V., Calvani M., Butterfield D.A. (2006) Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease. J. Neurosci. Res. 84, 398-408.
76. Perluigi M., Joshi G., Sultana R., Calabrese V., De Marco C., Coccia R., Cini C., Butterfield D.A. (2006) In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress. J. Neurosci. Res. 84, 418-426.
77. Mancuso C., Perluigi M., Cini C., De Marco C., Giuffrida Stella A.M., Calabrese V., (2006) Heme oxygenase and cyclooxygenase in the central nervous system: A functional interplay. J. Neurosci. Res. 84, 1385-1391.
78. Calabrese V., Sultana R., Scapagnini G., Guagliano E., Sapienza M., Bella R., Kanski J., Pennisi G., Mancuso C., Stella A.M., Butterfield D.A. (2006) Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid. Redox. Signal. 8, 1975-1986.
79. Mancuso C., Pani G., Calabrese V. (2006) Bilirubin: an endogenous scavenger of nitric oxide and reactive nitrogen species. Redox Rep. 11, 207-213.
80. Mancuso C., Scapagnini G., Curro D., Giuffrida Stella A.M., De Marco C., Butterfield D.A., Calabrese V. (2007) Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci. 12, 1107-1123.
81. Calabrese V., Guagliano E., Sapienza M., Panebianco M., Calafato S., Puleo E., Pennisi G., Mancuso C., Butterfield A.D., Giuffrida Stella A.M. (2007) Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. Neurochem Research 32, 757-773.
82. Calabrese V., Mancuso C., Ravagna A., Perluigi M., Cini C., De Marco C., Butterfield D.A., Giuffrida Stella A.M. (2007) In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state. J. Neurochem. 101, 709-717.
83. Piroddi M., Depunzio I., Calabrese V., Mancuso C., Aisa C.M., Binaglia L., Minelli A., Butterfield A.D., Galli F. (2007) Oxidatively-modified and glycated proteins as candidate pro-inflammatory toxins in uremia and dialysis patients. Amino Acids 32, 573-592.
84. Calabrese V. (2007) Highlight Commentary on “Redox proteomics analysis of oxidatively 3 modified proteins in G93A–SOD1 transgenic mice—A model of 4 familial amyotrophic lateral sclerosis”. Free Radical Biol. Med. 43, 160-162.
85. Calabrese V., Mancuso C., Calvani M., Rizzarelli E., Butterfield D.A., Giuffrida Stella A.M.. (2007) Nitric Oxide in the CNS: Neuroprotection versus Neurotoxicity. Nature Neuroscience 8, 766-775.
86. Calabrese V., Mancuso C., Sapienza M., Puleo E., Calafato S., Cornelius C., Finocchiaro M., Mangiameli A., Di Mauro M., Stella A.M., Castellino P. (2007) Oxidative stress and cellular stress response in diabetic nephropathy. Cell Stress Chaperones 12, 299-306.
87. Athanasiou A., Clarke A.B., Turner A.E, Kumaran N.M., Vakilpour S., Smith P.A., Bagiokou D., Bradshaw T.D, Westwell A.D, Fang L., Lobo D.N, Constantinescu C.S, Calabrese V., Loesch A. Alexander S.P, Clothier R.H, Kendall D.A, Bates T.E. (2007). Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and Biophysical Research Communications. 364, 131-137.
88. Mancuso C, Bates TE, Butterfield DA, Calafato S, Cornelius C, De Lorenzo A, Dinkova Kostova AT, Calabrese V. (2007) Natural antioxidants in Alzheimer's disease. Expert Opin Investig Drugs. 16, 1921-1931.
89. Calabrese V., Cornelius C., Mancuso C., Pennisi G., Calafato S., Bellia F., Bates T.E, Giuffrida Stella A.M., Schapira T., Dinkova Kostova A.T., Rizzarelli E. (2008) Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity. Neurochem. Res. 33, 2444-2471.
90. Mancuso C., Capone C., Ranieri S.C., Fusco S., Calabrese V., Eboli M.L., Preziosi P., Galeotti T., Pani G. (2008) Bilirubin as an endogenous modulator of neurotrophin redox signaling. J. Neurosci Res. 86, 1212-1230.
91. Calabrese V., Signorile A., Cornelius C., Mancuso C., Scapagnini G., Ventimiglia B., Ragusa N., Dinkova-Kostova A. (2008) Practical approaches to investigate redox regulation of heat shock protein expression and intracellular glutathione redox state. Methods Enzymol. 441, 83-110.
92. Calabrese V., Bates T.E., Mancuso C., Cornelius C., Ventimiglia B., Cambria M.T., Di Renzo L., De Lorenzo A., Dinkova-Kostova A.T. (2008) Curcumin and the cellular stress response in free radical-related diseases. Mol. Nutr. Food Res. 52, 1062-1073.
93. Calabrese V., Calafato S., Puleo E., Cornelius C., Sapienza M., Morganti P., Mancuso C. (2008) Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes. Clin. Dermatol. 26, 358-363.
94. Di Renzo L., Bertoli A., Bigioni M., Del Gobbo V., Premrov M.G., Calabrese V., Di Daniele N., De Lorenzo A. (2008) Body composition and -174G/C interleukin-6 promoter gene polymorphism: association with progression of insulin resistance in normal weight obese syndrome. Curr. Pharm. Des. 14, 2699-2706.
95. Calabrese V., Ientile R., Cornelius C., Scalia M., Cambria M.T., Ventimiglia B., Pennini G., Mancuso C., Butterfield D.A. (2008) Nutritional redox homeostasis and cellular stress response: Differential role of homocysteine and acetylcarnitine. In: Dietary modulation of cell sygnaling pathways. Surh Y.J., Dong Z., Cadenas E., Packer L. Eds. CRC Press, New York, N.Y. (USA)
96. Calabrese V., Calafato S., Cornelius C., Mancuso C., Dinkova-Kostova A. (2008) Heme oxygenase: A master vitagene involved in cellular stress response In: Enzymes and the Cellular Fight Against Oxidation. AM Eleuteri ed., Research Signpost 37/661 (2), Fort P.O., Trivandrum-695 023, Kerala, India. ISBN: 978-81-308-0239-8.
97. Calabrese V., Mancuso C., Cornelius C., Calafato M., Ventimiglia B., Butterfield D.A., Dinkova-Kostova A.T., Rizzarelli E. (2008) Reactive nitrogen species and cellular stress tolerance in aging and neurodegeneration: Role of vitagenes. In: Free Radical Pathophysiology, Alvarez S. and Evelson P. eds., 37/661 (2), pp. 345-367. Transworld Research Network, Kerala, India. ISBN 978-81-7895-311-3.
98. Calabrese V., Butterfield D.A., Stella A.M. (2008) Aging and oxidative stress response in the CNS. In: Development and Aging Changes in the Nervous System. Handbook of Neurochemistry and Molecular Neurobiology, Lajtha Abel, Perez-Polo J. Regino, Rossner Steffen (Eds.), 3rd ed., pp. 128-234. ISBN: 978-0-387-32670-2.
99. Calabrese V., Cornelius C., Mancuso C., Ientile R., Giuffrida Stella A.M., Butterfield D.A. (2008) Redox Homeostasis and Cellular Stress Response in Aging and Neurodegeneration. In: Free Radical and Antioxidant Protocols (2nd Edition), Uppu, R.M.; Murthy, S.N.; Pryor, W.A.; Parinandi, N.L. (Eds.), Humana Press, LA, USA.
100. Calabrese V., Perluigi M., Cornelius C., Coccia R., Di Domenico F., Mancuso C., Pennisi G., Dinkova-Kostova A.T. (2009) Phenolics in aging and neurodegenerative disorders. In: Phenolic Compounds of Plant Origin and Health: The Biochemistry behind their Nutritional and Pharmacological Value", C.G. Fraga Ed., Wiley & Sons, NY. USA.
101. Calabrese V., Cornelius C., Dinkova-Kostova A.T., Calabrese E.J. (2009) Vitagenes, cellular stress response and acetylcarnitine: relevance to hormesis. Biofactors 35, 146-160.
102. Calabrese V., Cornelius C., Mancuso C., Barone E., Calafato S., Bates T., Rizzarelli E., Kostova A.T. (2009) Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases. Front Biosci. 14, 376-397.
103. Bellia F., Calabrese V., Guarino F., Cavallaro M., Cornelius C., De Pinto V., Rizzarelli E. (2009) Carnosinase Levels in Aging Brain: Redox State Induction and Cellular Stress Response. Antioxid Redox Signal. 11, 2759-2775.
104. Calabrese V., Cornelius C., Rizzarelli E., Owen J.B., Dinkova-Kostova A.T., Butterfield D.A. (2009) Nitric oxide in cell survival: a Janus molecule. Antioxid. Redox. Signal. 11, 2717-2739.
105. Calabrese V., Cornelius C., Trovato A., Cambria M.T., Lo Cascio M.S., Di Rienzo L., Condorelli D., De Lorenzo A., Calabrese E.J. (2010) The hormetic role of dietary antioxidants in free radical-related diseases. Curr. Pharm. Des. 16: 8778-83.
106. Calabrese V, Cornelius C, Mancuso C, Lentile R, Stella AM, Butterfield DA. (2010) Redox homeostasis and cellular stress response in aging and neurodegeneration. Methods Mol. Biol. 610, 285-308.
107. De Lorenzo A, Noce A, Bigioni M, Calabrese V., Della Rocca DG, Di Daniele N, Tozzo C, Di Renzo L. (2010) The effects of Italian Mediterranean organic diet (IMOD) on health status. Curr Pharm Des. 16: 814-824.
108. Calabrese V., Cornelius C., Dinkova-Kostova AT., Calabrese E.J., Mattson MP. (2010) Cellular stress responses, the hormesis paradigm and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal. 13, 1763-1811.
109. Di Domenico F, Perluigi M, Butterfield DA, Cornelius C, Calabrese V. (2010) Oxidative Damage in Rat Brain During Aging: Interplay Between Energy and Metabolic Key Target Proteins. Neurochem Res. 35, 2184-2192.
110. Perluigi M, Di Domenico F, Giorgi A, Schininà ME, Coccia R, Cini C, Bellia F, Cambria MT, Cornelius C, Butterfield DA, Calabrese V. (2010) Redox proteomics in aging rat brain: Involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process. J Neurosci Res. 88, 3498-3507.
111. Calabrese V., Cornelius C., Giuffrida A.M., Calabrese E.J. (2010) Cellular stress responses, mitostress and carnitine insufficiencies as critical determinants in aging and neurodegenerative disorders: role of hormesis and vitagenes. Neurochem Res. 35, 1880-1915.
112. Calabrese V., Cornelius C., Maiolino L., Luca M., Chiaramonte R., Toscano M.A., Serra A. (2010) Oxidative stress, redox homeostasis and cellular stress response in ménière's disease: role of vitagenes. Neurochem Res. 35, 2208-2217.
113. Calabrese EJ, Mattson MP, Calabrese V. (2010) Dose response biology: the case of resveratrol. Hum Exp Toxicol. 29, 1034-1037.
114. Calabrese EJ, Mattson MP, Calabrese V. (2010) Resveratrol commonly displays hormesis:occurrence and biomedical significance. Hum Exp Toxicol. 29980-1015.
115. Cambria MT, Ragusa S, Calabrese V, Cambria A. (2011) Enhanced Laccase Production in White-Rot Fungus Rigidoporus lignosus by the Addition of Selected Phenolic and Aromatic Compounds. Appl Biochem Biotechnol. 163: 415-422.
116. Di Paola R., Impellizzeri D., Trovato Salinaro A., Mazzon E., Bellia F., Cavallaro M., Cornelius C., Vecchio G., Calabrese V., Rizzarelli E, Cuzzocrea S. Administration of carnosine in the treatment of acute spinal cord injury. (2011). Biochem Pharm 82, 1478-1489.
117. Pennisi G. , Cornelius C., Cavallaro M.M., Trovato Salinaro A., Cambria M.T., Pennisi M., Bella R., Milone P., Ventimiglia B., Migliore M.R., Di Renzo L., De Lorenzo A., Calabrese V. (2011). Redox regulation of cellular stress response in multiple sclerosis. Biochem Pharm 82, 1490-1499.
118. Scapagnini G, Caruso C, Calabrese V. Therapeutic Potential of Dietary Polyphenols against Brain Ageing and Neurodegenerative Disorders. (2011) Adv Exp Med Biol. 698: 27-35.
119. Calabrese V., Cornelius C., Cuzzocrea S., Iavicoli I., Rizzarelli E., Calabrese EJ. (2011) Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity. Mol Aspects of Med. 32: 279-304.
120. Bellia F., Vecchio G., Cuzzocrea S., Calabrese V., Rizzarelli E. (2011) Neuroprotection in oxidative driven diseases by carnosine. Mol Aspects of Med. 32: 258-266
121. Siciliano R, Barone E, Calabrese V, Rispoli V, Butterfield DA, Mancuso C. (2011) Experimental Research On Nitric Oxide And The Therapy Of Alzheimer Disease: A Challenging Bridge. CNS Neurol Disord Drug Targets. 10: 766-776.
122. Zhang Y, Ahn YH, Benjamin IJ, Honda T, Hicks RJ, Calabrese V, Cole PA, Dinkova-Kostova AT. (2011) HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway. Chem Biol. 18:1355-1361.
123. Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ. (2012) Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta. 1822: 753-783.
124. Di Renzo L, Bianchi A, Saraceno R, Calabrese V, Cornelius C, Iacopino L, Chimenti S, De Lorenzo A. (2012) -174G/C IL-6 gene promoter polymorphism predicts therapeutic response to TNF-α blockers. Pharmacogenet Genomics 22: 134-142.
125. Calabrese V, Cornelius C, Leso V, Trovato-Salinaro A, Ventimiglia B, Cavallaro M, Scuto M, Rizza S, Zanoli L, Neri S, Castellino P. (2012) Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes. Biochim Biophys Acta. 1822: 729-736.
126. Calabrese EJ, Iavicoli I, Calabrese V. (2012) Hormesis: why it is important to biogerontologists. Biogerontology.13: 215-235.
127. Cornelius C, Perrotta R, Graziano A, Calabrese EJ, Calabrese V. (2013) Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a "chi". Immun. Ageing. 10:15. doi:10.1186/1742-4933-10-15.
128. Cornelius C, Crupi R, Calabrese V, Graziano A, Milone P, Pennisi G, Radak Z, Calabrese EJ, Cuzzocrea S. (2013) Traumatic Brain Injury: Oxidative Stress and Neuroprotection. Antioxid Redox Signal. 19: 836-853.
129. Calabrese EJ, Calabrese V. (2013) Low dose radiation therapy (LD-RT) is effective in the treatment of arthritis: animal model findings. Int J Radiat Biol. 89: 287-294.
130. Calabrese EJ, Calabrese V. (2013) Reduction of arthritic symptoms by low dose radiation therapy (LD-RT) is associated with an anti-inflammatory phenotype. Int J Radiat Biol. 89: 278-286.
131. Calabrese EJ, Iavicoli I, Calabrese V. (2013) Hormesis: its impact on medicine and health. Hum Exp Toxicol. 32: 120-152.
132. Zhang Y., Dayalan Naidu S., R.V. Kostov, A. Pheely, V. Calabrese and A.T. Dinkova-Kostova (2013) Sulfhydryl-Reactive Phytochemicals as Dual Activators of Transcription Factors NRF2 and HSF1. In: D. R. Gang (ed.), 50 Years of Phytochemistry Research, Recent Advances in Phytochemistry 43, DOI 10.1007/978-3-319-00581-2_6, © Springer International Publishing (Switzerland).
133. Mancuso C, Santangelo R, Calabrese V. (2013) The heme oxygenase/biliverdin reductase system: a potential drug target in Alzheimer’s disease. J Biol Regul Homeost Agents. 27: 75-87.
134. Cornelius C, Trovato Salinaro A, Scuto M, Fronte V, Cambria MT, Pennisi M, Bella R, Milone P, Graziano A, Crupi R, Cuzzocrea S, Pennisi G, Calabrese V. (2013) Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes. Immun Ageing 10:41. doi: 10.1186/1742-4933-10-41.
135. Cornelius C, Graziano A, Calabrese EJ, Calabrese V. (2013) Hormesis and vitagenes in aging and longevity: mitochondrial control and hormonal regulation. Horm Mol Biol Clin Investig. 16:73-89.
136. Edrey YH, Oddo S, Cornelius C, Caccamo A, Calabrese V, Buffenstein R. (2014) Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. J Neurosci Res. 92: 195-205.
137. Davinelli S, Calabrese V, Zella D, Scapagnini G. (2014) Epigenetic nutraceutical diets in Alzheimer's disease. J Nutr Health Aging. Dec;18(9):800-5. doi: 10.1007/s12603-014-0520-6. PubMed PMID: 25389957.
138. Scapagnini G, Davinelli S, Kaneko T, Koverech G, Koverech A, Calabrese EJ, Calabrese V. (2014) Dose response biology of resveratrol in obesity. J Cell Commun Signal. 8: 385-391.
139. Calabrese V, Scapagnini G, Davinelli S, Koverech G, Koverech A, De Pasquale C, Salinaro AT, Scuto M, Calabrese EJ, Genazzani AR. (2014) Sex hormonal regulation and hormesis in aging and longevity: role of vitagenes. J Cell Commun Signal. 8: 369-384.
140. Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. (2014) Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 15: 449-461.
141. Cornelius C, Koverech G, Crupi R, Di Paola R, Koverech A, Lodato F, Scuto M, Salinaro AT, Cuzzocrea S, Calabrese EJ, Calabrese V. (2014) Osteoporosis and Alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling. Front Pharmacol. 5:120. doi:10.3389/fphar.2014.00120. eCollection 2014.
142. Trovato Salinaro A, Cornelius C, Koverech G, Koverech A, Scuto M, Lodato F, Fronte V, Muccilli V, Reibaldi M, Longo A, Uva MG, Calabrese V. (2014) Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease. Front Pharmacol. 5:129. doi:10.3389/fphar.2014.00129. eCollection 2014.
143. Currò M, Trovato-Salinaro A, Gugliandolo A, Koverech G, Lodato F, Caccamo D, Calabrese V, Ientile R. (2015) Resveratrol protects against homocysteine-induced cell damage via cell stress response in neuroblastoma cells. J Neurosci Res. 93: 149-156.
144. Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. (2014) Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 15: 449-461.
145. Cornelius C, Koverech G, Crupi R, Di Paola R, Koverech A, Lodato F, Scuto M, Salinaro AT, Cuzzocrea S, Calabrese EJ, Calabrese V. (2014) Osteoporosis and Alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling. Front Pharmacol. 5:120. doi:10.3389/fphar.2014.00120. eCollection 2014.
146. Trovato Salinaro A, Cornelius C, Koverech G, Koverech A, Scuto M, Lodato F, Fronte V, Muccilli V, Reibaldi M, Longo A, Uva MG, Calabrese V. (2014) Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease. Front Pharmacol. 5:129. doi:10.3389/fphar.2014.00129. eCollection 2014.
147. Calabrese V, Dattilo S, Petralia A, Parenti R, Pennisi M, Koverech G, Calabrese V, Graziano A, Monte I, Maiolino L, Ferreri T, Calabrese EJ. (2015) Analytical approaches to the diagnosis and treatment of aging and aging-related disease: redox status and proteomics. Free Radic Res. 49: 511-524.
148. Amadio M, Scapagnini G, Davinelli S, Calabrese V, Govoni S, Pascale A. (2015) Involvement of ELAV RNA-binding proteins in the post-transcriptional regulation of HO-1. Front Cell Neurosci. 8:459. doi: 10.3389/fncel.2014.00459.
149. Dattilo S, Mancuso C, Koverech G, Di Mauro P, Ontario ML, Petralia CC, Petralia A, Maiolino L, Serra A, Calabrese EJ, Calabrese V. (2015) Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases. Immun Ageing. 12:20. doi: 10.1186/s12979-015-0046-8. eCollection 2015.
150. Calabrese EJ, Dhawan G, Kapoor R, Iavicoli I, Calabrese V. (2015) What is hormesis and its relevance to healthy aging and longevity? Biogerontology 16:693-707.
151. Catino S, Paciello F, Miceli F, Rolesi R, Troiani D, Calabrese V, Santangelo R, Mancuso C. (2016) Ferulic Acid Regulates the Nrf2/Heme Oxygenase-1 System and Counteracts Trimethyltin-Induced Neuronal Damage in the Human Neuroblastoma Cell Line SH-SY5Y. Front Pharmacol. 8;6:305. doi: 10.3389/fphar.2015.00305.
152. Calabrese V., Davinelli S., Luca M., Zella D., Calabrese E.J., and Scapagnini G. (2015) Inflammaging, Oxidative Stress and Carnosine: Role of Hormetic Vitagenes. In: Imidazole Dipeptides : Chemistry, Analysis, Function and Effects. Food and Nutritional Components in Focus. January(8), pp. 238-256. EPUB eISBN: 978-1-78262-655-8. DOI:10.1039/9781782622611-00238.
153. Trovato A, Siracusa R, Di Paola R, Scuto M, Fronte V, Koverech G, Luca M, Serra A, Toscano MA, Petralia A, Cuzzocrea S, Calabrese V. (2016) Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer's disease pathogenesis. Neurotoxicology. 53:350-358.
154. Calabrese EJ, Dhawan G, Kapoor R, Iavicoli I, Calabrese V. (2016) HORMESIS: A Fundamental Concept with Widespread Biological and Biomedical Applications. Gerontology. 62:530-535.
155. Pennisi M, Crupi R, Di Paola R, Ontario ML, Bella R, Calabrese EJ, Crea R, Cuzzocrea S, Calabrese V. (2017) Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease. J Neurosci Res. 2017 Jul;95(7):1360-1372. doi: 10.1002/jnr.23986. Epub 2016 Nov 8
156. Calabrese V, Giordano J, Signorile A, Laura Ontario M, Castorina S, De Pasquale C, Eckert G, Calabrese EJ. (2016) Major pathogenic mechanisms in vascular dementia: Roles of cellular stress response and hormesis in neuroprotection. J Neurosci Res. 94:1588-1603.
157. Calabrese V, Giordano J, Ruggieri M, Berritta D, Trovato A, Ontario ML, Bianchini R, Calabrese EJ. (2016) Hormesis, cellular stress response, and redox homeostasis in autism spectrum disorders. J Neurosci Res. 2016 Dec;94(12):1488-1498. doi: 10.1002/jnr.23893.
158. Trovato A, Siracusa R, Di Paola R, Scuto M, Ontario ML, Bua O, Di Mauro P, Toscano MA, Petralia CC, Maiolino L, Serra A, Cuzzocrea S, Calabrese V. (2016) Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis. Immun Ageing. 13:23. doi: 10.1186/s12979-016-0078-8. eCollection 2016.
159. Barros, A.B., Bell, V., Ferrão, J., Calabrese, V., Fernandes, T.H. Mushroom biomass: Some clinical implications of β-glucans and enzymes. Current Research in Nutrition and Food Science 2016, 4, 37-47.
160. Calabrese V., Crea R. (2016). Potential prevention and treatment of Neurodegenerative Diseases: Olive polyphenols and hydroxytyrosol. Eur. J. Neurodegenerative Diseases 5: 81-108.
161. Barros A.B., Bell V., Ferrão J., Calabrese V., Fernandes T.H. (2016). Mushroom Biomass: Some Clinical Implications of β-Glucans and Enzymes. Current Res. Nutrition and Food Science 4: 37-47.
162. Paterniti I, Campolo M, Siracusa R, Cordaro M, Di Paola R, Calabrese V, Navarra M, Cuzzocrea S, Esposito E. (2017) Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson's disease. PLoS One. 12(4):e0174470.
163. Calabrese V, Giordano J, Crupi R, Di Paola R, Ruggieri M, Bianchini R, Ontario ML, Cuzzocrea S, Calabrese EJ. (2017) Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state. J Neurosci Res. 95:1182-1193.
164. Calabrese E.J., Calabrese V., Giordano J. (2017) The role of hormesis in the functional performance and protection of neural systems. Brain Circulation 3: 1-13.
165. Wang D., Calabrese E.J., Lian B., Lin Z., Calabrese V. (2017) Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine. Pharmacol Ther. Nov 8. pii: S0163-7258(17)30263-2. doi:10.1016/j.pharmthera.2017.10.013.
166. Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, Milenkovic D, Mohajeri MH, Sijben J, Solomon A, Spencer JPE, Thuret S, Vanden Berghe W, Vauzour D, Vellas B, Wesnes K, Willatts P, Wittenberg R, Geurts L. (20017) Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing Res Rev. 42:40-55.
167. Calabrese V, Santoro A, Monti D, Crupi R, Di Paola R, Latteri S, Cuzzocrea S, Zappia M, Giordano J, Calabrese EJ, Franceschi C. (2017) Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis. Free Radic Biol Med. 115: 80-91.
168. Peters V, Schmitt CP, Weigand T, Klingbeil K, Thiel C, van den Berg A, Calabrese V, Nawroth P, Fleming T, Forsberg E, Wagner AH, Hecker M, Vistoli G. (2017) Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift. J Enzyme Inhib Med Chem. 32(1):1102-1110.
169. Trovato Salinaro A, Pennisi M, Di Paola R, Scuto M, Crupi R, Cambria MT, Ontario ML, Tomasello M, Uva M, Maiolino L, Calabrese EJ, Cuzzocrea S, Calabrese V. (2018) Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer's disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms. Immun Ageing. 2018 Feb 14;15:8. doi: 10.1186/s12979-017-0108-1.
170. Calabrese EJ, Iavicoli I, Calabrese V, Cory-Slechta DA, Giordano J. (2018) Elemental mercury neurotoxicity and clinical recovery of function: A review of findings, and implications for occupational health. Environ Res. 9;163:134-148. doi: 10.1016/j.envres.2018.01.021.
171. Calabrese V, Santoro A, Monti D, Crupi R, Di Paola R, Latteri S, Cuzzocrea S, Zappia M, Giordano J, Calabrese EJ, Franceschi C. Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis. Free Radic Biol Med. 2018 Feb 1;115:80-91. doi: 10.1016/j.freeradbiomed.2017.10.379.
172. Calabrese V, Santoro A, Trovato Salinaro A, Modafferi S, Scuto M, Albouchi F, Monti D, Giordano J, Zappia M, Franceschi C, Calabrese EJ. Hormetic approaches to the treatment of Parkinson's disease: Perspectives and possibilities. J Neurosci Res. 2018 96:1641-1662.
173. Albouchi F, Avola R, Dico GML, Calabrese V, Graziano ACE, Abderrabba M, Cardile V. Melaleuca styphelioides Sm. Polyphenols Modulate Interferon Gamma/Histamine-Induced Inflammation in Human NCTC 2544 Keratinocytes. Molecules. 2018 Oct 2;23(10). pii: E2526. doi: 10.3390/molecules23102526.
174. Ferreiro E, Pita IR, Mota SI, Valero J, Ferreira NR, Fernandes T, Calabrese V, Fontes-Ribeiro CA, Pereira FC, Rego AC. Coriolus versicolor biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus. Oncotarget. 2018 31(68):32929-32942.
175. Peters V, Calabrese V, Forsberg E, Volk N, Fleming T, Baelde H, Weigand T, Thiel C, Trovato A, Scuto M, Modafferi S, Schmitt CP. Protective Actions of Anserine Under Diabetic Conditions. Int J Mol Sci. 2018 13;19(9). pii: E2751. doi: 10.3390/ijms19092751.
176. Miquel S, Champ C, Day J, Aarts E, Bahr BA, Bakker M, Bánáti D, Calabrese V, Cederholm T, Cryan J, Dye L, Farrimond JA, Korosi A, Layé S, Maudsley S, Milenkovic D, Mohajeri MH, Sijben J, Solomon A, Spencer JPE, Thuret S, Vanden Berghe W, Vauzour D, Vellas B, Wesnes K, Willatts P, Wittenberg R, Geurts L. Poor cognitive ageing: Vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing Res Rev. 2018 42:40-55.
177. Wang D, Calabrese EJ, Lian B, Lin Z, Calabrese V. Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine. Pharmacol Ther. 2018 Apr;184:42-50.
178. Pilipenko V, Narbute K, Amara I, Trovato A, Scuto M, Pupure J, Jansone B, Poikans J, Bisenieks E, Klusa V, Calabrese V. GABA-containing compound gammapyrone protects against brain impairments in Alzheimer's disease model male rats and prevents mitochondrial dysfunction in cell culture. J Neurosci Res. 2019 97:708-726.
179. Alamo A, Condorelli RA, Mongioì LM, Cannarella R, Giacone F, Calabrese V, La Vignera S, Calogero AE. Environment and Male Fertility: Effects of Benzo-α-Pyrene and Resveratrol on Human Sperm Function In Vitro. J Clin Med. 2019 Apr 25;8(4). pii: E561.
180. Modafferi S, Ries M, Calabrese V, Schmitt CP, Nawroth P, Kopf S, Peters V. Clinical Trials on Diabetic Nephropathy: A Cross-Sectional Analysis. Diabetes Ther. 2019 10: 229-243.
181. Concetta Scuto M, Mancuso C, Tomasello B, Laura Ontario M, Cavallaro A, Frasca F, Maiolino L, Trovato Salinaro A, Calabrese EJ, Calabrese V. Curcumin, Hormesis and the Nervous System. Nutrients. 2019 Oct 10;11(10). pii: E2417. doi: 10.3390/nu11102417.
182. Lo Dico G.M., Ulrici A., Pulvirenti A., Cammilleri G., Macaluso A., Vella A., Giaccone V., Lo Cascio G. , Graci S., Scuto M., Trovato Salinaro A., Calabrese V., Lo Dico R., Ferrantelli V. (2019) Multivariate statistical analysis of the polyphenols content for the discrimination of honey produced in Sicily (Southern Italy). Journal of Food Composition and Analysis 82, 103225.
183. Calabrese EJ, Bhatia TN, Calabrese V, Dhawan G, Giordano J, Hanekamp YN, Kapoor R, Kozumbo WJ, Leak RK. Cytotoxicity models of Huntington's disease and relevance of hormetic mechanisms: A critical assessment of experimental approaches and strategies. Pharmacol Res. 2019 Dec;150:104371. doi: 10.1016/j.phrs.2019.104371.
184. Scuto M, Di Mauro P, Ontario ML, Amato C, Modafferi S, Ciavardelli D, Trovato Salinaro A, Maiolino L, Calabrese V. Nutritional Mushroom Treatment in Meniere's Disease with Coriolus versicolor: A Rationale for Therapeutic Intervention in Neuroinflammation and Antineurodegeneration. Int J Mol Sci. 2019 Dec 31;21(1). pii: E284. doi: 10.3390/ijms21010284.
185. Amara I, Timoumi R, Annabi E, Di Rosa G, Scuto M, Najjar MF, Calabrese V, Abid-Essefi S. Di (2-ethylhexyl) phthalate targets the thioredoxin system and the oxidative branch of the pentose phosphate pathway in liver of Balb/c mice. Environ Toxicol. 2020 Jan;35(1):78-86.
186. Calabrese EJ, Calabrese V, Tsatsakis A, Giordano JJ. HORMESIS AND GINKGO BILOBA (GB): Numerous Biological Effects of GB are Mediated via Hormesis. Ageing Res Rev. 2020 Jan 10:101019. doi: 10.1016/j.arr.2020.101019.
187. Amara I, Salah A, Timoumi R, Annabi E, Scuto M, Trovato A, Neffati F, Calabrese V, Abid-Essefi S. Effect of di(2-ethylhexyl) phthalate on Nrf2-regulated glutathione homeostasis in mouse kidney. Cell Stress Chaperones. 2020, Jun 4. doi: 10.1007/s12192-020-01127-8.
188. Di Rosa G, Brunetti G, Scuto M, Trovato Salinaro A, Calabrese EJ, Crea R, Schmitz-Linneweber C, Calabrese V, Saul N. Healthspan Enhancement by Olive Polyphenols in C. elegans Wild Type and Parkinson's Models. Int J Mol Sci. 2020, 21 (11):E3893. doi: 10.3390/ijms21113893.
189. Flanagan E, Lamport D, Brennan L, Burnet P, Calabrese V, Cunnane SC, de Wilde MC, Dye L, Farrimond JA, Emerson Lombardo N, Hartmann T, Hartung T, Kalliomäki M, Kuhnle GG, La Fata G, Sala-Vila A, Samieri C, Smith AD, Spencer JPE, Thuret S, Tuohy K, Turroni S, Vanden Berghe W, Verkuijl M, Verzijden K, Yannakoulia M, Geurts L, Vauzour D. Nutrition and the ageing brain: Moving towards clinical applications. Ageing Res Rev. 2020, 62:101079. doi: 10.1016/j.arr.2020.101079.
190. Brunetti G, Di Rosa G, Scuto M, Leri M, Stefani M, Schmitz-Linneweber C, Calabrese V, Saul N. Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans. Int J Mol Sci. 2020, 21(7):2588. doi: 10.3390/ijms21072588.
191. Amara I, Scuto M, Zappalà A, Ontario ML, Petralia A, Abid-Essefi S, Maiolino L, Signorile A, Trovato Salinaro A, Calabrese V. Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells. Int J Mol Sci. 2020, 21(6):2138. doi: 10.3390/ijms21062138.
192. Leri M, Scuto M, Ontario ML, Calabrese V, Calabrese EJ, Bucciantini M, Stefani M. Healthy Effects of Plant Polyphenols: Molecular Mechanisms. Int J Mol Sci. 2020, 21(4):1250. doi: 10.3390/ijms21041250.
193. Calabrese EJ, Tsatsakis A, Agathokleous E, Giordano J, Calabrese V. Does Green Tea Induce Hormesis? Dose Response. 2020 18(3):1559325820936170.
194. Scuto M, Trovato Salinaro A, Modafferi S, Polimeni A, Pfeffer T, Weigand T, Calabrese V, Schmitt CP, Peters V. Carnosine Activates Cellular Stress Response in Podocytes and Reduces Glycative and Lipoperoxidative Stress. Biomedicines. 2020 8(6):177. doi: 10.3390/biomedicines8060177.
195. Amara I, Salah A, Timoumi R, Annabi E, Scuto M, Trovato A, Neffati F, Calabrese V, Abid-Essefi S. Effect of di(2-ethylhexyl) phthalate on Nrf2-regulated glutathione homeostasis in mouse kidney. Cell Stress Chaperones. 2020 25(6):919-928.
196. Calabrese EJ, Mattson MP, Dhawan G, Kapoor R, Calabrese V, Giordano J. Hormesis: A potential strategic approach to the treatment of neurodegenerative disease. Int Rev Neurobiol. 2020;155:271-301. doi: 10.1016/bs.irn.2020.03.024.
197. Calabrese V, Scuto M, Salinaro AT, Dionisio G, Modafferi S, Ontario ML, Greco V, Sciuto S, Schmitt CP, Calabrese EJ, Peters V. Hydrogen Sulfide and Carnosine: Modulation of Oxidative Stress and Inflammation in Kidney and Brain Axis. Antioxidants (Basel). 2020 Dec 18;9(12):1303. doi: 10.3390/antiox9121303.
198. Siracusa R, Scuto M, Fusco R, Trovato A, Ontario ML, Crea R, Di Paola R, Cuzzocrea S, Calabrese V. Anti-inflammatory and Anti-oxidant Activity of Hidrox in Rotenone-Induced Parkinson's Disease in Mice. Antioxidants (Basel). 2020 Sep 3;9(9):824. doi: 10.3390/antiox9090824. PMID: 32899274; PMCID: PMC7576486.
199. Amara I, Ontario ML, Scuto M, Lo Dico GM, Sciuto S, Greco V, Abid-Essefi S, Signorile A, Salinaro AT, Calabrese V. Moringa oleifera Protects SH-SY5YCells from DEHP-Induced Endoplasmic Reticulum Stress and Apoptosis. Antioxidants (Basel). 2021 Mar 29;10(4):532. doi: 10.3390/antiox10040532. PMID: 33805396; PMCID: PMC8065568.
200. Siracusa R, Schaufler A, Calabrese V, Fuller PM, Otterbein LE. Carbon Monoxide: from Poison to Clinical Trials. Trends Pharmacol Sci. 2021 May;42(5):329-339. doi: 10.1016/j.tips.2021.02.003. Epub 2021 Mar 26. PMID: 33781582; PMCID: PMC8134950.
201. Calabrese EJ, Calabrese V, Giordano J. Demonstrated hormetic mechanisms putatively subserve riluzole-induced effects in neuroprotection against amyotrophic lateral sclerosis (ALS): Implications for research and clinical practice. Ageing Res Rev. 2021 May;67:101273. doi: 10.1016/j.arr.2021.101273. Epub 2021 Feb 8. PMID: 33571705.
202. Calabrese EJ, Calabrese V, Giordano J. Putative hormetic mechanisms and effects of atypical antipsychotic agents: Implications for study design and clinical psychopharmacotherapeutics. Chem Biol Interact. 2021 Jan 5;333:109327. doi: 10.1016/j.cbi.2020.109327. Epub 2020 Nov 23. PMID: 33242461.
203. Fusco R., Salinaro A.T., Siracusa R., D'amico R., Impellizzeri D., Scuto M., Ontario M.L., Crea R., Cordaro M., Cuzzocrea S., Di Paola R., Calabrese V. Hidrox counteracts cyclophosphamide-induced male infertility through nrf2 pathways in a mouse model. Antioxidants, 10(5),778, 2021.
204. Cordaro M., Salinaro A.T., Siracusa R., D'amico R., Impellizzeri D., Scuto M., Ontario M.L., Interdonato L., Crea R., Fusco R., Cuzzocrea S., Di Paola R., Calabrese V. Hidrox® and endometriosis: Biochemical evaluation of oxidative stress and pain. Antioxidants 10 (5) 720, 2021.
205. D'Amico R, Trovato Salinaro A, Cordaro M, Fusco R, Impellizzeri D, Interdonato L, Scuto M, Ontario ML, Crea R, Siracusa R, Cuzzocrea S, Di Paola R, Calabrese V. Hidrox and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain. Antioxidants (Basel). 2021 Jun 29;10(7):1046.
206. D'Amico R, Trovato Salinaro A, Fusco R, Cordaro M, Impellizzeri D, Scuto M, Ontario ML, Lo Dico G, Cuzzocrea S, Di Paola R, Siracusa R, Calabrese V. Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury. Antioxidants (Basel). 2021 Jun 2;10(6):898. doi: 10.3390/antiox10060898.
207. Calabrese V., Scuto M., Calabrese E.J. Hormesis, Resilience and Mental Health: Enhancing Public Health and Therapeutic Options. In: J. Sholl and S. Rattan (eds.), Explaining Health Across the Sciences, Healthy Ageing and Longevity 12, 28:497-520, 2021. https://doi.org/10.1007/978-3-030-52663-4_28.
208. Calabrese V., Trovato A., Scuto M., Ontario M., Tomasello M., Perrotta M., Calabrese E.J. Resilience signaling and hormesis in brain health and disease. In: Human Aging: From Cellular Mechanisms to Therapeutic Strategies. Academic Press, 9:155-172, 2021. https://doi.org/10.1016/B978-0-12-822569-1.00012-3.
209. Calabrese V., Trovato A., Scuto M., Ontario M.L., Rampulla F., Zimbone V., La Mantia I., Maiolino L., Greco V., Sciuto S., Crea R., Calabrese E.J., Dionisio G. Food for Brain. In: S. Rattan and G. Kaur (eds.), Nutrition, Food and Diet in Health and Longevity. Healthy Aging and Longevity 14. ISBN 978-3-030-83017-5.
210. Modafferi S, Zhong X, Kleensang A, Murata Y, Fagiani F, Pamies D, Hogberg HT, Calabrese V, Lachman H, Hartung T and Smirnova L. Gene environment interactions in developmental neurotoxicity - a case study of synergy between chlorpyrifos and CHD8 knockout in human BrainSpheres. Environ Health Perspect. 2021 Jul;129(7):77001. doi: 10.1289/EHP8580.
211. Calabrese EJ, Agathokleous E, Kapoor R, Dhawan G, Calabrese V. LUTEOLIN AND HORMESIS. Mech Ageing Dev. 2021 Aug 14:111559. doi: 10.1016/j.mad.2021.111559.
212. Calabrese EJ, Agathokleous E, Kapoor R, Dhawan G, Kozumbo WJ, Calabrese V. Metformin-enhances resilience via hormesis. Ageing Res Rev. 2021 Aug 5;71:101418. doi: 10.1016/j.arr.2021.101418. Epub ahead of print. PMID:34365027.
213. Scuto M, Trovato Salinaro A, Caligiuri I, Ontario ML, Greco V, Sciuto N, Crea R, Calabrese EJ, Rizzolio F, Canzonieri V, Calabrese V. Redox modulation of vitagenes via plant polyphenols and vitamin D: Novel insights for chemoprevention and therapeutic interventions based on organoid technology. Mech Ageing Dev. 2021 Aug 3;199:111551. doi: 10.1016/j.mad.2021.111551.
214. Calabrese EJ, Agathokleous E, Calabrese V. Ferulic acid and hormesis: Biomedical and environmental implications. Mech Ageing Dev. 2021 Sep;198:111544. doi: 10.1016/j.mad.2021.111544.
215. Cordaro M, Salinaro AT, Siracusa R, D'Amico R, Impellizzeri D, Scuto M, Ontario ML, Cuzzocrea S, Di Paola R, Fusco R, Calabrese V. Key Mechanisms and Potential Implications of <i>Hericium erinaceus</i> in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease. Antioxidants (Basel). 2021 Oct 22;10(11):1664. doi: 10.3390/antiox10111664. PMID: 34829535; PMCID: PMC8615045.
216. Calabrese EJ, Agathokleous E, Kapoor R, Dhawan G, Kozumbo WJ, Calabrese V. Metformin-enhances resilience via hormesis. Ageing Res Rev. 2021 Nov;71:101418. doi: 10.1016/j.arr.2021.101418. Epub 2021 Aug 5. PMID: 34365027.
217. D'Angeli F, Guadagni F, Genovese C, Nicolosi D, Trovato Salinaro A, Spampinato M, Mannino G, Lo Furno D, Petronio Petronio G, Ronsisvalle S, Sipala F, Falzone L, Calabrese V. Anti-Candidal Activity of the Parasitic Plant <i>Orobanche crenata</i> Forssk. Antibiotics (Basel). 2021 Nov 9;10(11):1373. doi: 10.3390 Antibiotics 10111373. PMID: 34827311; PMCID: PMC8615231.
218. D'Amico R, Cordaro M, Siracusa R, Impellizzeri D, Trovato Salinaro A, Scuto M, Ontario ML, Crea R, Cuzzocrea S, Di Paola R, Fusco R, Calabrese V. Wnt/β-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox<sup>®</sup>. Biomedicines. 2021 Nov 13;9(11):1683. doi: 10.3390/ Biomedicines 9111683. PMID: 34829912; PMCID: PMC8615925.
219. Di Paola R, Modafferi S, Siracusa R, Cordaro M, D'Amico R, Ontario ML, Interdonato L, Salinaro AT, Fusco R, Impellizzeri D, Calabrese V, Cuzzocrea S. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation. Int J Mol Sci. 2022 Apr 17;23(8):4429. doi: 10.3390/ijms23084429. PMID: 35457246; PMCID: PMC9024626.
220. Calabrese EJ, Calabrese V. Enhancing health span: muscle stem cells and hormesis. Biogerontology. 2022 Apr;23(2):151-167. doi: 10.1007/s10522-022-09949-y. Epub 2022 Mar 7. PMID: 35254570.
221. Impellizzeri D, Fusco R, Genovese T, Cordaro M, D'Amico R, Trovato Salinaro A, Ontario ML, Modafferi S, Cuzzocrea S, Di Paola R, Calabrese V, Siracusa R. Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect. Antioxidants (Basel). 2022 Feb 17;11(2):406. doi:10.3390/antiox11020406. PMID: 35204289; PMCID: PMC8869697.
222. Cammilleri G, Calabrese V, Accordino L, Pantano L, Migliazzo A, Galluzzo FG, Parrino V, Brunone A, Lo Dico GM, Bacchi E, Giangrosso G, Calvacca PF, Ferrantelli V. Toxic metals and total lipids comparison between wild and farmed fish of South mediterranean. Nat Prod Res. 2022 Feb 8:1-11. doi:10.1080/14786419.2022.2037588. Epub ahead of print. PMID: 35133242.
223. Ontario ML, Siracusa R, Modafferi S, Scuto M, Sciuto S, Greco V, Bertuccio MP, Trovato Salinaro A, Crea R, Calabrese EJ, Di Paola R, Calabrese V. Potential prevention and treatment of neurodegenerative disorders by olive polyphenols and hidrox. Mech Ageing Dev. 2022 Apr;203:111637. doi: 10.1016/j.mad.2022.111637. Epub 2022 Feb 2. PMID: 35122769.
224. Davinelli S, Saso L, D'Angeli F, Calabrese V, Intrieri M, Scapagnini G. Astaxanthin as a Modulator of Nrf2, NF-κB, and Their Crosstalk: Molecular Mechanisms and Possible Clinical Applications. Molecules. 2022, 27(2):502. doi: 10.3390/molecules27020502. PMID: 35056816; PMCID: PMC8779084.
225. Bucciantini M, Leri M, Scuto M, Ontario M, Trovato Salinaro A, Calabrese EJ, Calabrese V, Stefani M. Xenohormesis underlyes the anti-aging and healthy properties of olive polyphenols. Mech Ageing Dev. 2022 Mar;202:111620. doi:10.1016/j.mad.2022.111620. Epub 2022 Jan 13. PMID: 35033546.
226. Scuto M, Ontario ML, Salinaro AT, Caligiuri I, Rampulla F, Zimbone V, Modafferi S, Rizzolio F, Canzonieri V, Calabrese EJ, Calabrese V. Redox modulation by plant polyphenols targeting vitagenes for chemoprevention and therapy: Relevance to novel anti-cancer interventions and mini-brain organoid technology. Free Radic Biol Med. 2022 Feb 1;179:59-75. doi:10.1016/j.freeradbiomed.2021.12.267. Epub 2021 Dec 18. PMID: 34929315.
227. Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Calabrese V. Human dental pulp stem cells and hormesis. Ageing Res Rev. 2022 Jan;73:101540. doi:10.1016/j.arr.2021.101540. Epub 2021 Dec 8. PMID: 34890824.
228. Calabrese EJ, Calabrese V, Dhawan G, Kapoor R, Giordano J. Hormesis and neural stem cells. Free Radic Biol Med. 2022 Jan;178:314-329. doi:10.1016/j.freeradbiomed.2021.12.003. Epub 2021 Dec 4. PMID: 34871764.
229. Calabrese EJ, Calabrese V, Giordano J. Brain health promotion: Tactics within a strategic approach based upon valid, yet evolving scientific evidence. Mech Ageing Dev. 2022 Jan;201:111605. doi: 10.1016/j.mad.2021.111605. Epub 2021 Nov 16. PMID: 34798081.
230. Calabrese, E.J., Agathokleous, E., Kapoor, R., Dhawan, G., Calabrese, V. Stem cells and hormesis. Current Opinion in Toxicology 2022, 30,100340.
231. Galluzzo, F.G., Cumbo, V., Cammilleri, G., Calabrese, V., Pulvirenti, A., Cicero, N., Pantano, L., Mascetti, A., Lo Cascio, G., Bacchi, E., Macaluso, A., Vella, A., Seminara, S., Ferrantelli, V. Fatty Acids Composition of Stomach Oil of Scopoli’s Shearwater (Calonectris diomedea) from Linosa’s Colony. 2022, 12 (9), 1069.
232. Cammilleri G, Calabrese V, Vella A, Macaluso A, Bacchi E, Pantano L, Galluzzo FG, Oddo A, Giangrosso G, Ferrantelli V, Brunone M. Essential and non-essential elements in white lupin (Lupinus albus L.) cultivated in Southern Italy. Nat Prod Res. 2022 Aug 3:1-5. doi:10.1080/14786419.2022.2107641.
233. Scuto M, Modafferi S, Rampulla F, Zimbone V, Tomasello M, Spano' S, Ontario ML, Palmeri A, Trovato Salinaro A, Siracusa R, Di Paola R, Cuzzocrea S, Calabrese EJ, Wenzel U, Calabrese V. Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular basis to therapy. Mechanisms of Ageing and Development, 2022, 205:111686. doi: 10.1016/j.mad.2022.111686.
234. Calabrese, E.J., Calabrese, V. Hormesis and Epidermal Stem Cells. Dose-Response, 2022, 20(3):15593258221119911. doi: 10.1177/15593258221119911.
235. Corbi G, Ali S, Intrieri M, Modaferri S, Calabrese V, Davinelli S, Scapagnini G. Association Between Beta-Carotene Supplementation and Mortality: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Medicine, 2022, 9:872310. doi: 10.3389/fmed.2022.872310.
236. Siracusa R, Voltarelli VA, Salinaro AT, Modafferi S, Cuzzocrea S, Calabrese EJ, Di Paola R, Otterbein LE, Calabrese V. NO, CO and H2S: A trinacrium of bioactive gases in the brain. Biochemical Pharmacology, 2022, 202:115122. doi: 10.1016/j.bcp.2022.115122.
237. Peycheva K, Panayotova V, Stancheva R, Makedonski L, Merdzhanova A, Cammilleri G, Ferrantelli V, Calabrese V, Cicero N, Fazio F. Effect of steaming on chemical composition of Mediterranean mussel (Mytilus galloprovincialis): Evaluation of potential risk associated with human consumption. Food Science and Nutrition, 2022, 10(9):3052-3061. doi: 10.1002/fsn3.2903.
238. Calabrese, E.J., Dhawan, G., Kapoor, R., Agathokleous, E., Calabrese, V. Hormesis: Wound healing and keratinocytes. Pharmacological Research, 2022, 183:106393. doi: 10.1016/j.phrs.2022.106393.
239. Calabrese, E.J., Dhawan, G., Kapoor, R., Agathokleous, E., Calabrese, V. Hormesis: wound healing and fibroblasts. Pharmacological Research, 2022, 184:106449. doi:10.1016/j.phrs.2022.106449.
240. Bacchi E, Cammilleri G, Tortorici M, Galluzzo FG, Pantano L, Calabrese V, Vella A, Macaluso A, Dico GML, Ferrantelli V, Brunone M. First Report on the Presence of Toxic Metals and Metalloids in East Asian Bullfrog (Hoplobatrachus rugulosus) Legs Foods, 2022, 11(19):3009. doi:10.3390/foods11193009.
241. Cordaro M, Modafferi S, D'Amico R, Fusco R, Genovese T, Peritore AF, Gugliandolo E, Crupi R, Interdonato L, Di Paola D, Impellizzeri D, Cuzzocrea S, Calabrese V, Di Paola R, Siracusa R. Natural Compounds Such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice. Biomedicines, 2022, 10(10):2505. doi:10.3390/biomedicines10102505.
242. Anfuso CD, Cosentino A, Agafonova A, Zappalà A, Giurdanella G, Trovato Salinaro A, Calabrese V, Lupo G. Pericytes of Stria Vascularis Are Targets of Cisplatin-Induced Ototoxicity: New Insights into the Molecular Mechanisms Involved in Blood-Labyrinth Barrier Breakdown. Int. J. Mol. Sciences, 2022, 23(24):15790. doi: 10.3390/ijms232415790.
243. Wetzel C, Pfeffer T, Bulkescher R, Zemva J, Modafferi S, Polimeni A, Salinaro AT, Calabrese V, Schmitt CP, Peters V. Anserine and Carnosine Induce HSP70-Dependent H2S Formation in Endothelial Cells and Murine Kidney Antioxidants, 2022, 12(1):66. doi:10.3390/antiox12010066.
244. Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Calabrese V. Human dental pulp stem cells and hormesis. Ageing Res Rev. 2022, 73:101540. doi:10.1016/j.arr.2021.101540.
245. Calabrese, E.J.,Kapoor, R.,Dhawan, G., Calabrese, V. Hormesis mediates platelet-rich plasma and wound healing. Wound Repair and Regeneration, 2023, 31(1):56-68. doi:10.1111/wrr.13060.
246. Calabrese V, Jacob UM, Fritsch T, Abdelhameed AS, Osakabe N. Redoxomics in Ageing and Neurodegenerative Disorders: From Bench to Clinics. Transl Med UniSa. 2023 Dec 29;25(2):50-51. doi: 10.37825/2239-9747.1045.
247. Interdonato L, Marino Y, Impellizzeri D, D'Amico R, Siracusa R, Fusco R, Cammilleri G, Pantano L, Modafferi S, Abdelhameed AS, Fritsch T, Rashan LJ, Cuzzocrea S, Calabrese V, Cordaro M, Di Paola R. Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on <i>Boswellia</i> Sacra gum resin. Front Physiol. 2024 Jan 5;14:1320960. doi: 10.3389/fphys.2023.1320960.
248. Calabrese EJ, Hayes AW, Pressman P, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Quercetin induces its chemoprotective effects via hormesis. Food Chem Toxicol. 2024 Feb;184:114419. doi: 10.1016/j.fct.2023.114419. Epub 2023 Dec 23.
249. Di Paola R, Siracusa R, Fusco R, Ontario M, Cammilleri G, Pantano L, Scuto M, Tomasello M, Spanò S, Salinaro AT, Abdelhameed AS, Ferrantelli V, Arcidiacono A, Fritsch T, Lupo G, Signorile A, Maiolino L, Cuzzocrea S, Calabrese V. Redox Modulation of Meniere Disease by Coriolus Versicolor Treatment, a Nutritional Mushroom Approach with Neuroprotective Potential. Curr Neuropharmacol. 2023 Dec 8. doi: 10.2174/1570159X22666231206153936. Epub ahead of print. PMID: 38073105.
250. Morganti P, Coltelli MB, Gagliardini A, Lazzeri A, Morganti G, Simonetti G, Fritsch T, Calabrese V, Fusco A, Donnarumma G. Biopolymer- and Natural Fiber-Based Biomimetic Tissues to Realize Smart Cosmeceuticals and Nutraceuticals Using an Innovative Approach. Pharmaceutics. 2023 Oct 24;15(11):2525. doi:10.3390/pharmaceutics 15112525.
251. Osakabe N, Modafferi S, Ontario ML, Rampulla F, Zimbone V, Migliore MR, Fritsch T, Abdelhameed AS, Maiolino L, Lupo G, Anfuso CD, Genovese E, Monzani D, Wenzel U, Calabrese EJ, Vabulas RM, Calabrese V. Polyphenols in Inner Ear Neurobiology, Health and Disease: From Bench to Clinics. Medicina (Kaunas). 2023 Nov 20;59(11):2045. doi: 10.3390/medicina59112045. PMID: 38004094;
252. Osakabe N, Fushimi T, Fujii Y, Calabrese V. Procyanidins and sensory
nutrition; Do procyanidins modulate homeostasis via astringent taste receptors? Biosci Biotechnol Biochem. 2023 Nov 1:zbad154. doi: 10.1093/bbb/zbad154. Epub ahead of print.
253. Calabrese E, Hayes AW, Pressman P, Kapoor R, Dhawan G, Calabrese V, Agathokleous E. Polyamines and hormesis: Making sense of a dose response dichotomy. Chem Biol Interact. 2023 Dec 1;386:110748. doi:
10.1016/j.cbi.2023.110748. Epub 2023 Oct 8.
254. Calabrese EJ, Osakabe N, Di Paola R, Siracusa R, Fusco R, D'Amico R,
Impellizzeri D, Cuzzocrea S, Fritsch T, Abdelhameed AS, Wenzel U, Franceschi C, Calabrese V. Hormesis defines the limits of lifespan. Ageing Res Rev. 2023 Nov;91:102074. doi: 10.1016/j.arr.2023.102074. Epub 2023 Sep 13.
255. Cammilleri G, Calabrese V, Pantano L, Brunone M, Galluzzo FG, Pulvirenti A, Fritsch T, Bongiorno C, Macaluso A, Ferrantelli V. Polyphenols of white lupin (<i>Lupinus albus</i> L.) seeds cultivated in Southern Italy by a LC-HRMS method. Nat Prod Res. 2023 Sep 7:1-5. doi: 10.1080/14786419.2023.2245535. Epub ahead of print.
256. Calabrese EJ, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Moringa induces its beneficial effect via hormesis. Nutr Res Rev. 2023 Sep 4:1-10. doi: 10.1017/S0954422423000161. Epub ahead of print.
257. Cosentino A, Agafonova A, Modafferi S, Trovato Salinaro A, Scuto M, Maiolino L, Fritsch T, Calabrese EJ, Lupo G, Anfuso CD, Calabrese V. Blood-Labyrinth Barrier in Health and Diseases: Effect of Hormetic Nutrients. Antioxid Redox Signal. 2023 Oct 25. doi: 10.1089/ars.2023.0251.
258. Calabrese EJ, Pressman P, Hayes AW, Dhawan G, Kapoor R, Calabrese V, Agathokleous E, Iavicoli I, Giordano J. Hormesis, biological plasticity, and implications for clinical trial research. Ageing Res Rev. 2023 Sep;90:102028. doi: 10.1016/j.arr.2023.102028.
259. La Torre GL, Vadalà R, Cicero N, Lo Cascio G, Cicero A, Calabrese V,
Ferrantelli V, Ingallina C, Salvo A. Evaluating the inhibition effect of a novel bio-packaging on histamine content in mackerel (<i>Scomber scombrus</i>): a new strategy with environment respect. Nat Prod Res. 2023 Jul 12:1-6. doi: 10.1080/14786419.2023.2235711.
260. Fushimi T, Hirahata C, Hiroki K, Fujii Y, Calabrese V, Suhara Y, Osakabe N. Activation of transient receptor potential channels is involved in reactive oxygen species (ROS)-dependent regulation of blood flow by (-)-epicatechin tetramer cinnamtannin A2. Biochem Pharmacol. 2023 Aug;214:115682. doi: 10.1016/j.bcp.2023.115682.
261. Calabrese EJ, Pressman P, Hayes AW, Dhawan G, Kapoor R, Agathokleous E, Manes P, Calabrese V. Naringin commonly acts via hormesis. Sci Total Environ. 2023 Oct 20;896:164728. doi: 10.1016/j.scitotenv.2023.164728. Epub 2023 Jun 7.
262. Calabrese EJ, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Rhodiola rosea and salidroside commonly induce hormesis, with particular focus on longevity and neuroprotection. Chem Biol Interact. 2023 Aug 1;380:110540. doi: 10.1016/j.cbi.2023.110540. Epub 2023 May 9.
263. Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Calabrese V. Protective effects of alpha lipoic acid (ALA) are mediated by hormetic mechanisms. Food Chem Toxicol. 2023 Jul;177:113805. doi: 10.1016/j.fct.2023.113805. Epub 2023 May 10.
264. Impellizzeri D, Tomasello M, Cordaro M, D'Amico R, Fusco R, Abdelhameed AS, Wenzel U, Siracusa R, Calabrese V, Cuzzocrea S, Di Paola R. Memophenol<sup>TM</sup> Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer's Disease Rat. Int J Mol Sci. 2023 Apr 8;24(8):6938. doi: 10.3390/ijms24086938.
265. D'Amico R, Tomasello M, Impellizzeri D, Cordaro M, Siracusa R, Interdonato L, Abdelhameed AS, Fusco R, Calabrese V, Cuzzocrea S, Di Paola R. Mechanism of Action of Natural Compounds in Peripheral Multiorgan Dysfunction and Hippocampal Neuroinflammation Induced by Sepsis. Antioxidants (Basel). 2023 Mar 3;12(3):635. doi: 10.3390/antiox12030635.
266. Calabrese EJ, Pressman P, Hayes AW, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Lithium and hormesis: Enhancement of adaptive responses and biological performance via hormetic mechanisms. J Trace Elem Med Biol. 2023 Jul;78:127156. doi: 10.1016/j.jtemb.2023.127156.
267. Calabrese E, Pressman P, Agathokleous E, Dhawan G, Kapoor R, Calabrese V. Boron enhances adaptive responses and biological performance via hormetic mechanisms. Chem Biol Interact. 2023 May 1;376:110432. doi:10.1016/j.cbi.2023.110432.
268. Torrisi F, D'Aprile S, Denaro S, Pavone AM, Alberghina C, Zappalà A,
Giuffrida R, Salvatorelli L, Broggi G, Magro GG, Calabrese V, Vicario N, Parenti R. Epigenetics and Metabolism Reprogramming Interplay into Glioblastoma: Novel Insights on Immunosuppressive Mechanisms. Antioxidants (Basel). 2023 Jan 18;12(2):220. doi: 10.3390/antiox12020220.
269. Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Dhawan V, Manes PK, Calabrese V. Nitric oxide and hormesis. Nitric Oxide. 2023 Apr 1;133:1-17. doi: 10.1016/j.niox.2023.02.001.
270. Cammilleri G, Galluzzo FG, Pulvirenti A, Pantano L, Calabrese V, Gentile A, Cumbo V, Macaluso A, Macaluso V, Vella A, Ferrantelli V. Toxic metals in Loggerhead sea turtles (<i>Caretta caretta</i>) stranded freshly dead along Sicilian coasts. Vet Q. 2023 Dec;43(1):1-10. doi: 10.1080/01652176.2023.2169781.
271. Calabrese V, Jacob UM, Fritsch T, Abdelhameed AS, Osakabe N. Redoxomics in Ageing and Neurodegenerative Disorders: From Bench to Clinics. Transl Med UniSa. 2023 Dec 29;25(2):50-51. doi: 10.37825/2239-9747.1045.
272. Calabrese EJ, Pressman P, Hayes AW, Kapoor R, Dhawan G, Agathokleous E, Calabrese V. Taurine induces hormesis in multiple biological models: May have transformative implications for overall societal health. Chem Biol Interact. 2024 Mar 1;392:110930. doi: 10.1016/j.cbi.2024.110930.
273. Osakabe N, Shimizu T, Fujii Y, Fushimi T, Calabrese V. Sensory Nutrition and Bitterness and Astringency of Polyphenols. Biomolecules. 2024 Feb 17;14(2):234. doi: 10.3390/biom14020234.
274. Calabrese EJ, Hayes AW, Pressman P, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Flavonoids commonly induce hormetic responses. Arch Toxicol. 2024 Feb 17. doi: 10.1007/s00204-024-03684-8.
275. Galluzzo FG, Cammilleri G, Pulvirenti A, Mannino E, Pantano L, Calabrese V, Buscemi MD, Messina EMD, Alfano C, Macaluso A, Ferrantelli V. Determination of Mycotoxins in Plant-Based Meat Alternatives (PBMAs) and Ingredients after Microwave Cooking. Foods. 2024 Jan 21;13(2):339. doi: 10.3390/foods13020339.
276. Interdonato L, Marino Y, Impellizzeri D, D'Amico R, Siracusa R, Fusco R, Cammilleri G, Pantano L, Modafferi S, Abdelhameed AS, Fritsch T, Rashan LJ, Cuzzocrea S, Calabrese V, Cordaro M, Di Paola R. Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on <i>Boswellia</i> Sacra gum resin. Front Physiol. 2024 Jan 5;14:1320960. doi: 10.3389/fphys.2023.1320960.
277. Calabrese EJ, Nascarella M, Pressman P, Hayes AW, Dhawan G, Kapoor R, Calabrese V, Agathokleous E. Hormesis determines lifespan. Ageing Res Rev. 2024 Feb;94:102181. doi: 10.1016/j.arr.2023.102181.
278. Calabrese EJ, Hayes AW, Pressman P, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. Quercetin induces its chemoprotective effects via hormesis. Food Chem Toxicol. 2024 Feb;184:114419. doi: 10.1016/j.fct.2023.114419. Epub 2023 Dec.
279. Calabrese EJ, Pressman P, Hayes AW, Dhawan G, Kapoor R, Agathokleous E, Calabrese V. RUTIN, a widely consumed flavonoid, that commonly induces hermetic effects. Food Chem Toxicol. 2024 May;187:114626. doi: 10.1016/j.fct.2024.114626. Epub 2024 Mar 29. PMID: 38556157.
280. Osakabe N, Fushimi T, Fujii Y, Calabrese V. Procyanidins and sensory
nutrition; do procyanidins modulate homeostasis via astringent taste receptors? Biosci Biotechnol Biochem. 2024 Mar 22;88(4):361-367. doi: 10.1093/bbb/zbad154. PMID: 37930827.
281. Calabrese V, Osakabe N, Khan F, Wenzel U, Modafferi S, Nicolosi L, Fritsch T, Jacob UM, Abdelhameed AS, Rashan L. Frankincense: A neuronutrient to approach Parkinson's disease treatment. Open Med (Wars). 2024 Jun 17;19(1):20240988. doi:10.1515/med-2024-0988.
282. Calabrese V, Wenzel U, Piccoli T, Jacob UM, Nicolosi L, Fazzolari G, Failla G, Fritsch T, Osakabe N, Calabrese EJ. Investigating hormesis, aging, and neurodegeneration: From bench to clinics. Open Med (Wars). 2024 Jun 17;19(1):20240986. doi: 10.1515/med-2024-0986.
283. La Torre GL, Vadalà R, Cicero N, Lo Cascio G, Cicero A, Calabrese V, Ferrantelli V, Ingallina C, Salvo A. Evaluating the inhibition effect of a novel bio-packaging on histamine content in mackerel (<i>Scomber scombrus</i>): a new strategy with environment respect. Nat Prod Res. 2024 Jun;38(12):2123-2128. doi: 10.1080/14786419.2023.2235711.
284. Scuto M, Rampulla F, Reali GM, Spanò SM, Trovato Salinaro A, Calabrese V. Hormetic Nutrition and Redox Regulation in Gut-Brain Axis Disorders. Antioxidants (Basel). 2024 Apr 18;13(4):484. doi: 10.3390/antiox13040484.
285. Cosentino A, Agafonova A, Modafferi S, Trovato Salinaro A, Scuto M, Maiolino L, Fritsch T, Calabrese EJ, Lupo G, Anfuso CD, Calabrese V. Blood-Labyrinth Barrier in Health and Diseases: Effect of Hormetic Nutrients. Antioxid Redox Signal. 2024 Mar;40(7-9):542-563. doi: 10.1089/ars.2023.0251.
286. Candore G, Accardi G, Aiello A, Baggio G, Bellini T, Calabrese V, Carreca AP, Carreca I, Masucci A, Cattaneo M, Dato S, Bona DD, Fabris L, Gambino C, Lorenzo GD, Francescschi C, Ligotti ME, Manfrinato MC, Puca AA, Tamburello M, Vassallo R, Caruso C. Sex and Gender in Ageing and Longevity: Highlights From an International Course. Transl Med UniSa. 2024 Feb 27;26(1):15-29. doi: 10.37825/2239-9747.1049.
287. Osakabe N, Shimizu T, Fujii Y, Fushimi T, Calabrese V. Sensory Nutrition and Bitterness and Astringency of Polyphenols. Biomolecules. 2024 Feb 17;14(2):234. doi: 10.3390/biom14020234. PMID: 38397471; PMCID: PMC10887135.
288. Interdonato L, Marino Y, Impellizzeri D, D'Amico R, Siracusa R, Fusco R, Cammilleri G, Pantano L, Modafferi S, Abdelhameed AS, Fritsch T, Rashan LJ, Cuzzocrea S, Calabrese V, Cordaro M, Di Paola R. Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on <i>Boswellia</i> Sacra gum resin. Front Physiol. 2024 Jan 5;14:1320960. doi: 10.3389/fphys.2023.1320960. PMID: 38250661; PMCID: PMC10797063.
289. Modafferi S, Lupo G, Tomasello M, Rampulla F, Ontario M, Scuto M, Salinaro AT, Arcidiacono A, Anfuso CD, Legmouz M, Azzaoui FZ, Palmeri A, Spano S, Biamonte F, Cammilleri G, Fritsch T, Sidenkova A, Calabrese E, Wenzel U, Calabrese V. Antioxidants, Hormetic Nutrition, and Autism. Curr Neuropharmacol. 2024;22(7):1156-1168. doi: 10.2174/1570159X21666230817085811.